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Drug use may increase the risk of Kovid-19 breakthrough infection


Breakthrough Infection: If you are a frequent use of tobacco or marijuana, if you are addicted to alcohol or drugs, you are at higher risk of contracting the corona virus despite a ‘breakthrough’ infection or complete vaccination. This disclosure has come from research published in World Psychiatry. The researchers concluded after analyzing 580,000 people who had taken both doses of the vaccine in the US.

Intoxication can increase the breakthrough infection of Kovid-19

Research has found that drug abusers are at a higher risk of getting infected with the corona virus even after using both doses of the Kovid-19 vaccine. Drug abuse disorder also known as drug addiction is a type of disorder i.e. dependence on marijuana, alcohol, cocaine, narcotic substances and tobacco.

Drug addiction reduces the effect of the vaccine

Researchers say that the effect of the vaccine in drug addicts may be reduced by excessive use of marijuana, alcohol, cocaine, drugs and tobacco. He wrote, “Addicts are at higher risk of COVID-19 infection and adverse consequences of infection. Although the vaccine is highly effective against COVID-19, the vaccine’s effect in drug addicts is due to a weakened immune system.” may be less than that.”

Research showed that 3.6 percent of non-drug addicts were affected by breakthrough infection while in contrast 7 percent of people with drug addiction were affected by breakthrough infection. Researchers said that people consuming marijuana were at the highest risk, ie 7.8 percent showed breakthrough infection. At number two, 7.7 percent of people who used cocaine were involved and 7.2 percent of people who used alcohol had a breakthrough infection.

Marijuana proponents said that the research did not see that marijuana could be the reason behind the breakthrough cases. Significantly, the results of the research have come at a time when the World Health Organization has recommended the use of the third dose of Kovid-19 vaccine to those with weakened immune systems. A panel of experts from the World Health Organization is going to review the global data on booster doses in a meeting to be held on November 11.

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How dangerous is the delta variant for pregnant women who do not get the corona vaccine?


Delta Variant: A recent research has found that the delta variant can increase the risk of complications among women who are not vaccinated. Researchers analyzed severe illness of Kovid-19 in pregnant women from May 2020 to September 2021. Research has found that the corona delta variant is highly contagious.

Vaccination advice for pregnant women against Kovid

According to research published in the American Journal of Obstetrics and Gynecology, Kovid-19 was confirmed in 1515 pregnant women. Of them, 82 had serious cases and 11 required ventilator support. During this two pregnant women died. Research indicated that 5 percent of pregnant patients fought the serious disease of Kovid-19 by March 2021. Researchers say that pregnant women who have not been vaccinated are worried about their future.

Corona’s delta variant can increase the risk of problems

The research concluded that pregnant women after confirmation of the delta variant are more likely to develop serious disease and those who have not been vaccinated are at higher risk of hospitalization. Researchers urged pregnant women to get vaccinated because it is the best way to prevent Kovid-19. Last week the Centers for Disease Control and Prevention issued a warning asking pregnant women or those trying to become pregnant to get vaccinated against Kovid-19.

According to the CDC, as of September 27, more than 125,000 pregnant women have confirmed cases of Kovid-19. Of them, 22,000 had to be hospitalized due to severe infection and 161 died during this period. Despite the serious risk, the CDC reports that 31 percent of pregnant women aged 18-49 completed vaccination against COVID-19. The CDC wrote in its health advisory, “Pregnant women with symptoms of Kovid-19 have twice the risk of going to the ICU and the risk of death is increased by 70.”

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What should pregnant women do after receiving the Covid-19 vaccine? – VnExpress


Pregnant women should not be alone in the first three days after injection, strictly monitor their health, create psychological comfort for the best immune response.

Pregnant women are considered a special target group when receiving the Covid-19 vaccine. The pregnant woman’s body has to bear the double burden; The kidneys, liver, cardiovascular and respiratory systems work with greater intensity. After the injection, they experience the same side effects as normal people such as fever, fatigue, headache, chills, joint pain, increased pain sensation, swelling, redness, restlessness, etc. Pregnant women need to be very careful, monitor and treat promptly if there are severe side effects.

Master, Doctor Vu Nguyet Anh, Deputy Head of General Planning Department, Hanoi Obstetrics and Gynecology Hospital, recommends that the first three days after vaccination against Covid-19 pregnant women should not be alone because this is the body’s time. Side effects are often present. Pregnant women actively monitor their own health, eat nutritiously, get enough sleep, and feel comfortable to have the best immune response after vaccination.

If the fever is below 38.5 degrees after injection, loosen clothes, apply/wipe with a warm towel on the forehead, armpits, groin, drink enough water, do not catch cold, measure the temperature again after 30 minutes. If the fever is 38.5 degrees or higher or body aches, pain at the injection site, take antipyretic, ordinary pain reliever containing paracetamol according to the instructions of medical staff. In case the fever does not reduce or the fever is higher than 39 degrees, the pregnant woman should immediately notify the medical staff and go to the nearest medical facility.

In case of swelling, redness, pain, small lumps at the injection site, monitor health. If the swelling is bigger, the symptoms do not decrease, the pregnant woman should go to the doctor immediately. Do not apply, apply on painful swelling at the injection site of poultices from herbs, leaves or ointments…

Pregnant women with a schedule of tetanus and measles vaccinations should arrange to have them at least 14 days before the Covid-19 vaccine or 28 days after the Covid-19 vaccine.

Pregnant women in Hanoi get the Covid-19 vaccine. Photo: Giang Huy.

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Vaccination of 1.6 crore people completed in Karnataka, know the condition of rest of the states of South India


Karnataka has defeated South Indian states in the measures being taken to prevent corona infection. He has completed the vaccination of the largest number of people against Kovid-19. Out of the targeted population of 4.9 crore, 16 crore (32 per cent) people have got both doses of the vaccine. This was revealed on Monday morning from the data of the Covin Dashboard.

Karnataka beats southern states in terms of complete vaccination

According to the data, Karnataka ranks fifth in terms of people who have been fully vaccinated. States like Maharashtra, Uttar Pradesh, Gujarat and West Bengal are ahead of Karnataka in the country. The number of people who got the doses of both the vaccines in Maharashtra is 2.2 crore, in Uttar Pradesh 1.8 crore, in Gujarat 1.8 crore and in West Bengal is 16 million. In terms of proportion, Gujarat’s role (37 per cent) is better than Karnataka, while Maharashtra (24 per cent), West Bengal (23 per cent) and Uttar Pradesh 12 (per cent) are at the bottom of the line. If we look at the figures of people who have completed vaccination in the southern states, it is found that in Andhra Pradesh about 13 million people have taken both doses of the vaccine, in Tamil Nadu 1.1 crore and in Kerala 10 million people have completed the vaccination.

Out of 4.9 crore, 1.6 crore people got both doses of the vaccine

In Telangana, 67.4 lakh people have been protected from both doses of the Kovid-19 vaccine. Arundhati Chandrashekhar, Mission Director, National Health Mission, Karnataka said, “We are yet to cover 67 per cent of the target population in Karnataka with the second dose. The focus is now on covering the rest of the population for the second dose in the state and this In this connection, we are sending messages to take advantage of the facility of free vaccination. We are planning to run a special campaign and focus on the backward districts in vaccination. Senior health department officials said that to reduce the severity of the third wave, maximum people should be fully vaccinated with both doses.

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Why prolong the trial of Covid-19 vaccine for children?


AmericaThe US Food and Drug Administration (FDA) requires drug companies to monitor young volunteers for 6 months, instead of the two months as adults.

To date, hundreds of millions of adults have been vaccinated, proving that the Covid-19 vaccine is safe and effective. But these results cannot replace studies in children. For the childhood version of the vaccine, the scientists used data on both adults and separate trials in children.

Research in adults helps speed this process up. For people under the age of 12, the company doesn’t need to recruit up to 30,000 volunteers like previous large-scale trials. This is based on a mechanism called “immunomodulation”, whereby data show that for this age group, the immune response is comparable to that of adults.

This is how vaccine companies reach children. But in early August, the FDA required drug companies to monitor young volunteers for six months, instead of two months as adults. The agency also recommended that Pfizer and Moderna double the number of children ages 5 to 11 in the clinical trial.

In June, the CDC’s vaccine adviser reported a rare risk of heart inflammation following mRNA vaccination in adolescents. Symptoms are relatively mild, resolve quickly, and do not require too much treatment.

At Texas Children’s Hospital, pediatrician James Versalovic had no problem recruiting more volunteers for the Pfizer and Moderna study. The registration list on the website is very long. However, the extension of the test made the whole process take another month.

“We all agree that this is necessary, making the data stronger and building the confidence of parents across the country. It makes the test time longer, but only a little,” he said.

Tacori Taylor, 12 years old, vaccinated against Covid-19 in the city of Albuquerque, USA. Photo: NY Times

The trials of vaccines for children actually start with older volunteers. Dr Kari Simonsen, Pfizer’s head of research at Children’s Hospital & Medical Center in Omaha, explains: “Typically, every vaccine candidate for a child, even with another disease, is injected in humans. But we cannot conclude about safety or tolerability in children based on results from adults.”

This is a biological mechanism. According to Dr. Versalovic, “children are not miniature versions of adults”, they are completely separate individuals.

“Their bodies are developing, they will react differently (when vaccinated). We need to handle it in our own way,” added Versalovic.

By the time of testing in children, scientists will predict a dose that is safe enough to induce an immune response. Time and extent depend on each stage of development.

“In general, children have sensitive immune systems, so we think smaller doses will trigger the appropriate response,” Ms Chapman said.

As with any study, the pediatric dose of the Covid-19 vaccine goes through three phases of clinical trials before it is submitted to the FDA for approval.

The first phase, to check if the vaccine is safe, takes place in about 20 to 100 people.

Since this is an accelerated test, the scientists combined stages two and three so that multiple steps can be performed in parallel, Versalovic explained. At this time, experts monitor the safety and check whether the child’s immune system responds to the vaccine. They need hundreds or even thousands of young volunteers. Some injected the vaccine, others used a placebo as a control.

This stage is complete, the new pharmaceutical company can request FDA review and approval. After regulatory approval, the vaccine continues to be overseen by the CDC’s Advisory Council on Immunization Practices. The committee also makes recommendations on distribution, storage, shelf life and directions for use.

According to experts, during this time, adults need to protect children against Covid-19 by proactively immunizing themselves and wearing masks.

Dr. Scott Gottlieb, a former FDA commissioner and now a member of Pfizer’s board of directors, said the company will release the results of the trial in September, and is expected to submit an application to the regulator in October.

Thuc Linh (Follow CNN)

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Why are women more prone to side effects of the Kovid vaccine?


Covid-19 Vaccination: Side effects are a common occurrence with any vaccine. It does not put your health at any risk nor does it leave any long-term effect on the body. Mild illness may be experienced when infected with the corona virus, while other people may show absolutely no symptoms. Depending on your immune system and the body’s response to the external pathogen, symptoms are likely to appear, which can range from mild to severe.

Women at higher risk of side effects

Similar to corona infection, the vaccine can trigger symptoms that may be similar to the symptoms of Kovid. Given that the Kovid vaccine is a copy of the original virus, it triggers an immune response that resembles the immune response activated by corona infection. Common side effects of the vaccine range from fever, fatigue, nausea to body ache. Apart from that, many people may also experience itching, redness, swelling at the injection site, which goes away in a day or two.

According to the Centers for Disease Control and Prevention, research suggests that most reactions to the Kovid-19 vaccine are not as severe, but women report more side effects of the vaccine than men. Whenever someone gets a vaccine, the body’s immune system gets activated, which produces antibodies to fight harmful pathogens. This in turn causes the body’s inflammatory response, leading to side effects.

Common Side Effects of Kovid-19 Vaccine

Women are more likely to experience more unexpected side effects of the vaccine, such as an itchy red rash. Red rash appears at the injection site, as about 95 percent of the reaction occurs with Moderna’s vaccine. While the report suggests that women are at higher risk of side effects of the vaccine, it may be because they have stronger and healthier immune systems than men. Research has also claimed that women produce stronger antibodies than their male counterparts.

Some experts believe that women are more likely than men to report side-effects because of their behavioral factor as women are known to be more vocal about their illnesses than men. According to experts, the female hormone estrogen generally enhances and influences the response of the immune system. In contrast, the male hormone testosterone suppresses the immune system, which may be the main reason for women experiencing more side effects of the Kovid-19 vaccine.

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WHO accuses rich countries of prolonging Covid-19


WHO officials criticized the situation of rich countries collecting vaccines and drugs to treat Covid-19 causing the pandemic to continue to develop complicatedly around the world.

“This situation is not only unjust and unethical, but it also prolongs the pandemic, causing deadly consequences,” said epidemiologist Maria Van Kerkhove, the WHO’s Covid-19 technical team leader. (WHO), emphasized in the online press conference on September 7.

According to a WHO report, Africa has only received two doses of the Covid-19 vaccine for about 3% of the continent’s population. At the current rate of vaccination, about 80% of African countries in September will not be able to protect the 10% of the population most at risk of infection.

Mike Ryan, director of the WHO’s health emergencies program, criticized high-income countries for not acting on their claims of ensuring equitable access to vaccines. “In fact, in a difficult situation, medicine is collected into the hands of a few countries and not shared,” he said.

According to statistics from the Center for Systems Science and Engineering (CSSE) of Johns Hopkins University, as of September 8, the world had recorded 221,706,278 cases of nCoV infection, including 4,582,737 deaths. confirmed death. In the past 28 days, the world has increased by more than 17.8 million infections and more than 273,000 deaths.

An Israeli woman is injected with the Covid-19 vaccine Pfizer-BioNTech in Dimona on February 21. Photo: Reuters.

A report from data research firm Airfinity shows that global production of Covid-19 vaccines reached 6.1 billion doses as of the end of August. The company estimates global vaccine production per month at 1.5 billion doses and total volume. World vaccine by the end of this year is likely to reach 12.2 billion doses.

Most vaccines are concentrated in rich countries. G7 members, including the UK, Canada, Germany, France, Italy, Japan and the US, have more than 300 million doses of Covid-19 vaccine left over and are expected to stockpile 1.2 billion doses before the end of the year.

At the beginning of August, WHO asked rich countries to delay the booster vaccination plan for at least two months, shifting the source of the vaccine to poor countries that are threatened by the Delta mutation. However, the booster injection plan is still being implemented in the US, UK and France.

In China, the government has deployed more than two billion doses of the Covid-19 vaccine with about 67% of the population having received two doses. The National Health Commission (NHC) estimates 1.09 billion people have received at least one dose of the vaccine. The national vaccination program is accelerating with the population aged 12 to 17, aggressively building “immunity barriers” in the community.

After the Delta outbreak in July with more than 1,300 infections in 15 provinces, China continued to successfully control community transmission with strong measures. NHC on September 7 recorded 36 more symptomatic infections nationwide and no suspected cases. As of September 7, the country has 95,064 infections and 4,636 deaths from Covid-19.

Japan recorded positive signals in controlling the fourth wave of Covid-19 when the number of weekly infections tended to decrease. The number of new infections on September 7 was 1,629, an increase of nearly 500 cases compared to the beginning of the week but a sharp decrease compared to the number of 2,909 infections 7 days ago.

However, the epidemic situation in Japan in general is still complicated. The capital Tokyo and some localities have the ability to extend the state of emergency after the deadline on September 12. The tough measure was applied in 21 provinces. The European Union (EU) is considering putting the country on a list of travel restrictions to prevent Covid-19 risks.

America continues to be the country most severely affected by the pandemic with more than 40.2 million infections and more than 651,000 deaths in nearly two years. Although about 53% of the US population is fully protected by vaccines and more than 1.3 million people have received booster shots, the number of deaths and infections in the US has skyrocketed in recent days because of the Delta mutation.

Health officials in this country are more concerned when 49 out of 50 states have detected the Mu strain that is contagious in the community. The new strain is said to be more resistant to the effects of the vaccine than the recent mutations of nCoV. The state of California has the highest number of Mu mutant infections in the country, most of which are concentrated in the city of Los Angeles.

In Southeast AsiaAs of September 7, the whole region has more than 10.6 million infections and more than 216,500 deaths, according to statistics from the Center for Strategy and International Studies (CSIS). The three epidemic regions with the most infections in the region are Indonesia with more than 4.1 million cases, the Philippines with more than 2.1 million cases and Malaysia with more than 1.8 million cases.

Indonesian President Joko Widodo on September 7 called on people to recognize that Covid-19 will persist despite the country’s improvement in disease control. From August 31 to September 5, Indonesia recorded 49,753 new infections and 3,370 deaths, down more than 21,000 infections and nearly 1,000 deaths compared to the period from August 25 to 30.

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China admits vaccination campaign is in trouble


Health officials said China faces increasing difficulties as vaccination rates slow, even though only 60% of the population is fully vaccinated.

“Recently, the vaccination program has become increasingly difficult to enter the latter stage,” said Zheng Zhongwei, director of the Health and Medical Technology Research and Development Center under China’s National Health Commission. said today.

Trinh did not specify what these difficulties were, but warned those who have not yet received the Covid-19 vaccine not to expect themselves to be protected by those who have been vaccinated, amid growing concern about the variant. Delta with high spread.

The official said that about 900 million people in China have received the full course of the vaccine, accounting for more than 60% of the total population of about 1.4 billion. He cited experts as saying that China may need to achieve a Covid-19 vaccination rate higher than 80% to achieve herd immunity.

A Chinese medical worker holds a container of the Covid-19 Vero Cell vaccine manufactured by Sinopharm at a vaccination site in Beijing on April 15. Photo: Reuters.

China in July-August injected about 13 million vaccines per day, lower than the June average of 19 million. Mr. Trinh estimated that by the end of October, China will complete the Covid-19 vaccine according to the usual regimen for 1.1 billion people, and at the same time give booster shots for some population groups such as the elderly and working people. high risk of nCoV infection.

People in China are advised to get a booster shot of the same type used before. Zheng said Chinese people may have other options if research shows that using a different vaccine yields results.

China has supplied about a billion doses of vaccines to the world. Chinese President Xi Jinping in August affirmed that the country would strive to deliver two billion doses of the Covid-19 vaccine to other countries in 2021.

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How long does herd immunity last after vaccination? – VnExpress


70% of the population vaccinated against Covid-19 will create herd immunity. Can herd immunity be created in other ways, and will it last or only be short-term according to the effectiveness of the vaccine? (Nguyen Nam Giang, HCMC).

Reply:

Herd immunity is when most people in a community have acquired immunity to an infectious disease (either through vaccination or prior illness). When a certain number of the population is immune, the infection cycle is broken, the virus is no longer easily transmitted from person to person. As a result, the chain of infection slows down or stops.

The concept of “generating herd immunity by allowing the virus to spread naturally” is completely wrong. Because, letting the virus grow freely leads to many people getting sick and dying, increasing the medical burden and causing genocide due to epidemics like in previous centuries. Natural herd immunity is certainly not the right strategy and option for Covid-19. Vaccination against Covid-19 is the best way to achieve herd immunity.

If there is herd immunity, we will protect those who cannot be vaccinated, those who are susceptible to disease and are prone to death, such as young children, the elderly, and people with weakened immune systems. The more people get vaccinated against Covid-19, the fewer people get sick and the more people in the community are protected.

Depending on the goals and disease patterns of each country, vaccine coverage needs to be between 70-95% of the population to achieve herd immunity (that is, the maximum number of people in that country who are vaccinated against the vaccine). 70-95% of the total population), making the virus no longer able to spread significantly to the remaining unvaccinated population.

For diseases controlled by vaccines (measles, diphtheria, varicella, etc.), herd immunity lasts as long as vaccine coverage remains large enough.

For the Covid-19 pandemic, in addition to vaccine coverage, the effectiveness of vaccines with different variants of the virus also affects herd immunity. Some experts around the world believe that it is difficult to achieve herd immunity anytime soon because the new Delta variant of nCoV can infect even vaccinated people.

People in Hanoi get vaccinated against Covid-19 during a large-scale vaccination campaign, in early August. Photo: Giang Huy

Master, Doctor Nguyen Hien Minh
Immunization Unit, Ho Chi Minh City University of Medicine and Pharmacy Hospital

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‘Do not collect any costs related to Covid-19 vaccination’


Deputy Minister Tuyen said this at Online conference with 63 provinces/cities on the progress of the Covid-19 vaccination campaign. 9/8 pm. He emphasized that “even organizations and individuals that voluntarily support the cost, the units that organize vaccination are not accepted”.

“The organization of vaccination does not create a request – give mechanism, and it is strictly forbidden to be negative in the vaccination organization. Heads of agencies, units and authorities at all levels must bear the main responsibility for prevention work. epidemics including vaccination against Covid-19,” said the deputy minister.

Mr. Tuyen said that over the past time, the Ministry of Health has allocated over 18 million doses of vaccine to institutes and localities to deploy vaccination. However, in some localities, the injection progress is slow compared to the allocated amount, such as Dong Nai, Tay Ninh, Tra Vinh, Binh Duong, Hau Giang, Ba Ria Vung Tau, Tien Giang, and Thanh Hoa.

The Deputy Minister asked all localities and units to speed up the vaccination schedule, not to wait or choose; but when the vaccine is on the way, it will be injected in that batch, “so that we can step by step ensure herd immunity”.

The unit injects vaccines with a low rate compared to the allocated number of vaccines, the Ministry of Health will announce on the mass media for people to know, monitor and supervise. The Ministry of Health proactively transferred those vaccines to other units and localities with high injection rates and fast injection rates.

“At that time, the Ministry of Health will not exchange back, but base on the remaining data to transfer. The view is to give priority to vaccines for Ho Chi Minh City and the southern provinces and cities with epidemics”, Mr. Tuyen said.

Deputy Minister of Health Do Xuan Tuyen held an online conference with 63 provinces/cities on the progress of implementing the Covid-19 vaccination campaign, on the afternoon of August 9. Photo: Tran Minh.

The Ministry of Health requires provinces and cities to approve the master plan on vaccination by July 30. However, until today, there are still localities that say that the province will not approve until August 5. The Deputy Minister requested localities to review and approve before August 15.

Localities arrange both fixed and mobile injection points, as many injection points as possible, avoiding the fact that some places receive tens of thousands of doses of vaccine but do not complete the injection for a whole week. At the same time, there is no limit to the number of injectors in one injection site.

“Inject as much as possible. One injection point is not necessarily only 100 doses a day but can be up to 200-300 or more, but must ensure compliance with anti-epidemic and vaccination safety, against negative in the vaccination,” said the deputy minister.

Regarding the transport of vaccines, Mr. Tuyen said that right after the allocation decision of the Ministry of Health and the vaccine was delivered to the warehouse, it was requested within 5 days by the Central Institute of Hygiene and Epidemiology, the Western Institute of Hygiene and Epidemiology. Nguyen and the Pasteur Institutes must supply to the localities. If more than 5 days, localities shall immediately report to the Ministry of Health.

“We have agreed with the leadership of the Ministry of National Defense that vaccines from the warehouses of the Central Institute of Hygiene and Epidemiology and Pasteur Institutes will be transported by the provincial military command in coordination with the Ministry of Health to deliver the vaccine to the locality. Therefore, localities do not worry about transporting vaccines,” Tuyen said.

After 5 months of vaccination, by the end of August 8, the country had injected more than 9.4 million doses, of which 8,458,225 people received 1 dose of vaccine and 967,400 people received 2 full doses of vaccine.

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